A standard intravenous fluid bag used in terrestrial applications
(Credit: NASA).
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IVGEN subassembly that purifies water coming from the space
vehicle. This subassembly also quantifies water cleanliness,
the water flow rate within the system, and mixing uniformity in
the IV solution.
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In the event of a medical emergency, astronauts
may require IV fluids to take drugs or rehydrate crewmembers that
are unable to swallow. If it is to be used intravenously, water
must be appropriately sterilized and mixed with the required drugs
or electrolytes. IVGEN’s goal is to meet the requirement for
IV fluid during exploration missions by constructing a filtration
system that will generate fluid using in situ resources. In this
effort, the fundamental requirement is that the filtration system
consumes less mass and volume than would the equivalent amount of
water the filtration system is able to produce.
Glenn was assigned the work to develop hardware
such as this because of the center’s expertise in microgravity
fluid physics. Glenn has partnered with ZIN Technologies to identify
water purification and mixing technologies that will function in
microgravity environments and will be easy to operate in emergency
situations. The team then tested prototype systems in a laboratory
environment, designed and tested flight-like hardware, and is currently
finishing hardware that will fly to the International Space Station
(ISS) in March 2010 for testing in April 2010.
Glenn researchers test the effectiveness of an IV fluid mixing
method on NASA's zero-gravity aircraft (Credit: NASA).
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In addition to fluid purification, IVGEN also contains
a subsystem to mix the purified fluid with appropriate pharmaceuticals.
Testing performed in GRC’s reduced gravity drop towers and
onboard reduced gravity aircraft demonstrated that microgravity
mixing is best accomplished using a rotating magnetic stir bar,
which is the technique implemented by IVGEN.
IVGEN will operate within the Microgravity Science Glovebox
(MSG) on ISS. This image shows the IVGEN test hardware assembled
inside of a MSG simulator.
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Using prototype and engineering hardware, the team
produced several liters fluid that passed all tests required by
the United States Pharmacopeia (USP) for IV medications.

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